STUDY OF ADHERENCE FOR HAART AND ITS CORRELATION WITH IMMUNOLOGICAL STATUS

A R KRISHNAMOHAN; KIRAN KUMAR P; C REVANTH KUMAR REDDY

Volume : VI, Issue : I, January - 2016

STUDY OF ADHERENCE FOR HAART AND ITS CORRELATION WITH IMMUNOLOGICAL STATUS

A R Krishnamohan, Kiran Kumar P, C Revanth Kumar Reddy

Abstract :

Back ground: Adherence rate of atleast 95% is required for optimum viral suppression and the prevention of viral mutation of drug resistant HIV strains , measured by CD4 cell and viral load counts Objective: To study the relation between adherence for HAART and the immunological improvement Materials and methods: This is a quantitative, retrospective univariate analytical study done in PLHIV and who were on HAART during the period of January 2008 to December 2013.The data is analysed using windows excel sheets and SPSS and univariate analysis was done for adherence rate and CD4 cell count. Result : 2593 patients ranged from 18–60 years the average age was 38 years. There were more males(1535/59.2%) than females(1040/40.2%)and transgenders(18/0.06%). Out of 2593, 83% had reported adherence level of >95%.and 82% of them achieved immunological recovery( cd4 >350) (p< 0.01). This shows the strong positive relation between the adherance rates and the immunological recovery in our setting. Conclusion: In a developing country like India focus on adherence rates >95% for HAART improves the immunological status of the patients and decrease in the mortality rates are observed