Study of Breast Carcinoma–Histopathological Correlation with ER, PR & Her 2 Neu Receptor Status–2 Year Experience of a Tertiary Care Centre in Central Uttar Pradesh

Suman Lata Verma; Swaraj Kumar Sharma; Chayanika Kala

Volume : VIII, Issue : I, January - 2018

Study of Breast Carcinoma–Histopathological Correlation with ER, PR & Her 2 Neu Receptor Status–2 Year Experience of a Tertiary Care Centre in Central Uttar Pradesh

Suman Lata Verma, Swaraj Kumar Sharma, Chayanika Kala

Abstract :

A total of 64 cases were included in this study.43.75% cases belonged to 41–50 years age with mean age of 48.90 years. 56(87.5%) cases were IDC, 3 cases lobular and 2 each of medullary and mucinous type respectively and 1 case of apocrine carcinoma. In BRG 54.68% cases belongs to grade II, 15.64% grade III and 17.18% to grade I. 54.68% cases were ER +, 42.18% were PR + and 29.68% were Her2 neu +. Most of the grade 1 and 2 tumors were ER positive and grade 3 were ER negative. Out of 64 cases 21 cases were belongs to luminal A, 14 cases were luminal B, 11 cases were her2 neu enriched and18 cases were triple negative phenotype. After applying chi square test, significant association between histological grade and molecular subtypes was seen & no significant association between age and molecular subtypes was seen.