STUDY OF CARDIAC DYSFUNCTION IN HYPOTHYROIDISM

Dr. Rajesh R. Karekar; Dr. Yogesh P. Rasal

Volume : VI, Issue : X, October - 2016

STUDY OF CARDIAC DYSFUNCTION IN HYPOTHYROIDISM

Dr. Rajesh R. Karekar, Dr. Yogesh P. Rasal

Abstract :

Background: Hypothyroidism is one of the most common endocrine problem encountered in clinical practice. Many thyroid disorders manifest as various cardiovascular symptoms and signs. At cellular level thyroid hormones act on cardiomyocytes and modifies cardiovascular functions like preload, afterload, myocardial contractility and excitability and oxygen consumption. Cardiac dysfunction can be assessed with the help of investigations like ECG, 2D ECHO and lipid profile in association with clinical symptoms and signs Restoration of euthyroid state in hypothyroidism restores cardiac function reducing cardiovascular morbidity and mortality. Results: In our study consisting of 42 patients, the age range was from 31–60 yrs. There was an overall female preponderance. Most common symptoms were of weight gain, lethargy, dry skin, and hoarseness of voice and adycardia and hypertension. Common ECG abnormalities were low voltage QRS, non specific ST T changes and QTc dispersion 2 D ECHO showed pericardial effusion, cardiac tamponade and diastolic LV dysfunction. Conclusion: Among 42 new cases of hypothyroidism, pericardial effusion was found in 19.42% patients. Diastolic dysfunction was seen in 26.56% patients. Thus any unexplained pericardial effusion should be screened for hypothyroidism.ECG abnormalities like low voltage QRS complex, QTc dispersion should be taken into consideration during therapeutic interventions.