Study of effect of various carbon sources on biomass and extracellular protein of Aspergillus fumigatus strain (MTCC 1811)

Sanyukta; Srivastava A K

Volume : V, Issue : X, October - 2015

Study of effect of various carbon sources on biomass and extracellular protein of Aspergillus fumigatus strain (MTCC 1811)

Sanyukta, Srivastava A K

Abstract :

The filamentous fungus Aspergillus fumigatus is well–known as a producer of primary metabolites and extracellular proteins. Extracellular proteins of filamentous fungi are important for biotechnological and biomedical applications. Aspergillus fumigatus not only comprises an important class of organisms that have significant commercial relevance to the biotechnology industry, but also is a fungal pathogen in immunocompromised patients. Thus, in this study, we analyzed the biomass and extracellular proteins of Aspergillus fumigatus under different culture conditions using sucrose, glucose, lactose or xylose as a main carbon source. The range of variation of biomass was from 14.24 gm/lit to 9.34 gm/lit when grown on 3.0% of glucose as sole carbon source at pH 4 and on 4.0% sucrose as carbon source at pH 7 respectively. Upon variation of carbon source concentration, the highest amount, 155.88µg/40ml of extracellular protein was produced when 3.5% of lactose was used as sole carbon source at pH 5.