STUDY OF EPITHELIAL CHANGES IN ADJOINING BREAST TISSUE OF MASTECTOMY SPECIMENS IN INFILTRATING DUCT CARCINOMA AND ITS CORRELATION WITH TUMOR SIZE AND GRADE

Lt Col (Dr) Puneet Baveja; Lt Col (Dr) Brahamjit singh

Volume : VII, Issue : V, May - 2017

STUDY OF EPITHELIAL CHANGES IN ADJOINING BREAST TISSUE OF MASTECTOMY SPECIMENS IN INFILTRATING DUCT CARCINOMA AND ITS CORRELATION WITH TUMOR SIZE AND GRADE

Lt Col Dr Puneet Baveja, Lt Col Dr Brahamjit Singh

Abstract :

Summary of the Paper Many east carcinoma probably arise in a multi–step fashion through a series of intermediate lesions i.e. ductal hyperplasia of usual type (HUT) to atypical ductal hyperplasia (ADH) to ducal carcinoma in situ (DCIS) and thereafter to invasive ductal carcinoma (IDC), each of which has a greater propensity of becoming malignant than the one that preceded it [1]. Keeping in mind the above, the study was undertaken to detect proliferative epithelial changes in the adjacent east parenchyma in 50 mastectomy specimens of infiltrating duct carcinoma. Out of 50 cases, 25 cases showed ductal hyper plastic changes in the form of HUT (Mild or moderate or florid), and DCIS. Mild hyper plastic changes were seen in 20 cases (40%). Moderate duct hyperplasia was seen in 10 (20%) cases and florid duct hyperplasia was seen in 3 (6%) cases. Foci of DCIS were noticed in 10 cases. No ADH was observed in our study.