STUDY OF HISTOPATHOLOGICAL PROFILE OF CENTRAL NERVOUS SYSTEM TUMOURS AT RIMS RAIPUR

Dr Chandrahas kant Choudhary; Dr Praveen Kumar; Dr Brajendra kumar

Volume : VII, Issue : IV, April - 2017

STUDY OF HISTOPATHOLOGICAL PROFILE OF CENTRAL NERVOUS SYSTEM TUMOURS AT RIMS RAIPUR

Dr Chandrahas Kant Choudhary, Dr Praveen Kumar, Dr Brajendra Kumar

Abstract :

The purpose of this study was to provide the spectrum of CNS tumours in RIMS RAIPUR.This cross–sectional study was carried out at Histopathology Department,RIMS RAIPUR over a period of 5 years. A total of 761 cases patients who were diagnosed with CNS tumours on histopathology, both benign and malignant, belonging to both genders, between the ages of 1–85 years, from Nov2012 to31.12.2016 were included in the study. Seven CNS tumour categories were as follows; tumours of neuroepithelial tissue (56.0%), tumours of the meninges (28.3%), tumour of the sellar region (2.6%), germ cell tumour (0.1), tumour of cranial and paraspinal nerves (5.4%), lymphomas and haematopoietic neoplasm (2.4%), metastatic tumours (4.9%), where histological types by age and gender showed great variability. Astrocytic tumours were the commonest neuroepithelial tumours (69.4%).Glioblastoma multiform forming the largest subtype of neuroepithelial tumours (40.4%) with a mean age at diagnosis being 47.1 years. Overall, males exceeded females in number of most of the CNS tumour types, however meningeal tumours were more frequently noted in females. Neuroepithelial tumours are commonest tumour and comprise more than half of all operated CNS tumours in our setup, followed by meningeal tumours. Glioblastoma multiforme is largest subtype of neuroepithelial tumour, and comprising 40.4% of all.