STUDY OF HISTOPATHOLOGICAL SPECTRUM OF LYMPH NODE BIOPSY IN PATIENTS IN THE AGE GROUP 11–70 YEARS IN A TERTIARY CARE CENTRE.

Volume : VII, Issue : VII, July - 2017

Dr. Sabari Devi, Dr. Partha Pratim Barman

Introduction: Lymphadenopathy is one of the commonest presentations of

patients in out patient department of any hospital . It is a common manifestation of a large

variety of disorders, both benign and malignant. Histopathological examination of the lymph

node biopsies is a gold standard test to confirm the diagnosis and also for detailed subtyping

of lymphomas. We designed this study in our population for histopathological evaluation of

lymph nodes that might be helpful for clinical management of these lesions.

Method: The present study was a prospective type of study. Total 89 numbers of patients

from September 2016 till March 2017 were recruited. All excised lymph node specimens

received in the Department of Pathology Gauhati Medical college and hospital constituted

the study material. The specimens were subjected to detailed histopathological examination.

In each case, pathological reactionpattern was studied carefully and documented.

Results: Out of total 89 cases, 33 cases were of granulomatous lymphadenitis,28 cases were

of non specific reactive hyperplasia, 4 cases were hodgkins lymphoma, 8 cases were non

hodgekins lymphoma , 13 cases were of metastatic lymph node and 1 each case of kikuchi

fujimoto’s disease ,castleman disease and rosai dorfman disease. Cervical lymph nodes were

most commonly biopsied group of lymph nodes in our study.

Conclusion: In present study the most common cause of lymph node biopsy was

granulomatous lymphadentits followed by nonspecific reactive hyperplasia. Among

neoplastic lesions metastatic lymph node disease accounted for maximum number of cases.