Study of hydralazine in controlling blood pressure in pregnancy induced hypertension

Dr. A.B. Dandapat; Dr.; R. Dash; Dr. D. Dash

Volume : VIII, Issue : VIII, August - 2018

Study of hydralazine in controlling blood pressure in pregnancy induced hypertension

Dr. A. B. Dandapat, Dr. , R. Dash, Dr. D. Dash

Abstract :

Background: Hypertensive disorders of pregnancy (HDP) are one of the most common medical complications of pregnancy. Hydralazine has been used for almost 40 years in the management of preeclampsia and is the prototype of peripherally acting anti–hypertensive drug. Objectives:1.To assess the efficacy of intravenous hydralazine in pregnancy induced hypertension.2.To assess the time taken and the number of doses required to achieve a target blood pressure of <140/90 mmHg.Methodology:It is an interventional study conducted in the department of Obstetrics & Gynaecology, VIMSAR,Burla from December 2015 to June 2017. 100 cases admitted to the labour room or OPD were randomly selected and enrolled after fulfilling inclusion and exclusion criteria. These 100 cases received intravenous hydralazine. Results: Most of the patients were in the age group 21–25 years (44%) followed by 26–30 years (35%).Intravenous hydralazine was found to be effective in controlling blood pressure in pregnancy induced hypertension which was found to be significant with p–value <0.05. Mean number of doses required to achieve the target BP was 1.96 and the time required for it was 29.51 minutes. Conclusions: Based on all the observations and analysis it was seen that intravenous hydralazine is effective in controlling blood pressure in pregnancy induced hypertension and no significant side–effects were observed for the drug.