Study of Myocardial Dysfunction in Patients of Cirrhosis of Liver

Sura Kishore Mishra; Indira Palo; Lily Devi; Mahesh Chandra Sahu

Volume : VII, Issue : X, October - 2017

Study of Myocardial Dysfunction in Patients of Cirrhosis of Liver

Sura Kishore Mishra, Indira Palo, Lily Devi, Mahesh Chandra Sahu

Abstract :

Objective: Cirrhosis is a very common ailment in India mostly caused by alcoholism, viral hepatitis and malnutrition. The clinical picture of patients with cirrhosis is dominated by the classical complications such as ascites, bleeding from esophageal varices, portal hypertension and encephalopathy. Here, Cardiovascular abnormalities have been reported by several investigators.

Methods: It is a cross sectional and observational study done on 60 patients admitted to MKCG Medical College, Berhampur,. 2014 to Dec. 2015. The associations of circulatory and cardiovascular dysfunction in cirrhosis patients were analyzed. All the demographic and clinical history of study populations were analyzed with SPPSS software.

Results: Diastolic dysfunction is measured by E/A ratio was prevalent LVED diameter, IV septal thickness, left ventricular posterior wall thickness were proportional to severity of liver cirrhosis. Electro physiologically, 38.33% patients of cirrhotic liver patients had prolonged QTc interval. Here, as far as cardiac abnormality were considered, we found QTc prolongation more in severe degree of

cirrhosis MELD score III (7 out of 10) 70%, than moderate (40%) MELD score II and mild (20%) MELD score I of cardiac QTc prolongation.

Conclusions; Diastolic dysfunction is a major criteria of cirrhotic cardiomyopathy which can be

diagnosed by electro and echo cardiography