STUDY OF SERUM MAGNESIUM LEVEL IN NEONATAL HYPERBILIRUBINEMIA– A HOSPITAL BASED STUDY

DR. ALAKESH CHOUDHURY; DR. SAURABH BORKOTOKI

Volume : VIII, Issue : V, May - 2018

STUDY OF SERUM MAGNESIUM LEVEL IN NEONATAL HYPERBILIRUBINEMIA– A HOSPITAL BASED STUDY

Dr. Alakesh Choudhury, Dr. Saurabh Borkotoki

Abstract :

Neonatal hyperbilirubinemia is the most common clinical condition that requires medical attention and hospital readmission in newborns. It is the yellowish discoloration of skin and sclera due to bilirubin. Deposition of unbounded bilirubin in the neuron memane causes permanent neuronal injury. Magnesium, a principally intracellular ion, increases in plasma may be due to extracellular movement resulting from generalized cellular injury including neurons and erythrocytes.

The aim of the study was to estimate and find the correlation between plasma magnesium and serum bilirubin levels in neonatal hyperbilirubinemia. Blood samples were collected from 30 full term neonates who were admitted with jaundice over a period from September 2017 to Feuary 2018 in neonatology unit,department of pediatrics, Jorhat Medical College& Hospital. There was a positive correlation between the plasma magnesium level and serum bilirubin level (r = 0.987 and P value is significant <0.0001). The study highlights the possibility of a neuroprotective role or compensatory mechanism of magnesium against the toxicity of increasing serum bilirubin.