Volume : V, Issue : X, October - 2015

Study of serum nitric oxide in insulin resistant subjects with varying degrees of metabolic syndrome

Dr. Parineeta Samant

Abstract :

 Metabolic syndrome is the primary metabolic disorder associated with insulin resistance which can affect health of endothelium. The aim of this study was to assess the association between insulin resistance and serum nitric oxide in patients with varying degrees of metabolic syndrome. Total 150 subjects were enrolled for the study and were divided into four groups based on the presence of metabolic syndrome components as per NCEP ATP III criteria. Anthropometric and biochemical parameters were studied in all the subjects. Insulin resistance was calculated using HOMA IR model. Serum nitric oxide levels were estimated using modified Griess method. Comparison of all biochemical parameters between control and study group II, III and IV showed significant difference (p<0.05) except for serum nitric oxide which statistically insignificant on compÃ¥ group III levels with group IV. These finding indicate presence of three MS component is enough to cause damage endothelium.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Dr. Parineeta Samant Study of serum nitric oxide in insulin resistant subjects with varying degrees of metabolic syndrome Indian Journal of Applied Research, Vol.5, Issue : 10 October 2015


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