Volume : X, Issue : VI, June - 2020

STUDY OF SERUM SMALL DENSE LDL IN TYPE 2 DIABETES MELLITUS PATIENTS AND ITS ASSOCIATION WITH CORONARY ARTERY DISEASE

Krunali D. Gaidhane, S. B. Asegaonkar, Minal S. Sonune, R. J. Shendye

Abstract :

AIM: Coronary heart disease is one of the most leading causes of death in this modern era. It has been found that diabetic patients are more prone for coronary heart disease and diabetic dyslipidemia is the main culprit. We aimed this study to find the association between lipid profile, sdLDL in patients of T2DM with and without CAD. MATERIAL AND METHOD: It was a case–control study conducted on 180 patients who were divided into three groups as randomly selected controls, patients with DM and CAD, and patients having DM without CAD. Blood samples were compared for lipid profile and sdLDL was calculated based on Friedwald’s equation. level of sdLDL particles among diabetic patients associated with (50.73 ± 15.56, p< 0.001) and without (50.12 ± 17.01, p<0.001) CAD and found that there is significant rise of sdLDL in DM patients compared with controls (24.72 ± 5.49). on compå the sdLDL–C among diabetic patients associated with and without CAD (Pearson chi square test, p=0.00 with Odds ratio 11.81 with 95% CI 3.3–41.0) which gives 11 times increased risk of raised sdLDL value in DM with CAD patients. CONCLUSION: sdLDL is proved to be the better index for the early detection and monitoring of cardiac health in diabetic individuals.

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Article: Download PDF    DOI : 10.36106/ijar  

Cite This Article:

STUDY OF SERUM SMALL DENSE LDL IN TYPE 2 DIABETES MELLITUS PATIENTS AND ITS ASSOCIATION WITH CORONARY ARTERY DISEASE, Krunali D. Gaidhane, S.B.Asegaonkar, Minal S. Sonune, R.J.Shendye INDIAN JOURNAL OF APPLIED RESEARCH : Volume-10 | Issue-6 | June-2020

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