STUDY OF THYROID DYSFUNCTION IN PATIENTS WITH TYPE 2 DIABETES MELLITUS

Midde Ranga Raja Rao; Madhu Babu koduru; M.L.S.J.SWARUP REDDY

Volume : VII, Issue : IX, September - 2017

STUDY OF THYROID DYSFUNCTION IN PATIENTS WITH TYPE 2 DIABETES MELLITUS

Midde Ranga Raja Rao, Madhu Babu Koduru, M. L. S. J. Swarup Reddy

Abstract :

AIMS AND OBJECTIVES – The study was undertaken with an objective to study the thyroid functions in Type 2 diabetics and to know the spectrum of thyroid dysfunction in Type 2 DM.

METHODS – A total of 140 patients with Type 2 DM who were diagnosed on the basis of American Diabetes Association (ADA) criteria or who were taking treatment for Diabetes were included in the study. All patients in the study underwent thyroid profile tests and also target organ evaluation for Diabetes. TPO–Ab, thyroid USG and FNAC were done wherever required. A detailed history and examination was done on these patients.

RESULTS – A total of 140 Type 2 DM patients were included in the study. Thyroid disorders were present in 31.42%. Low thyroid function was seen in 28 patients and hyper functioning of thyroid gland was noticed in 16 patients. Overt Hypothyroidism in 3, sub–clinical hypothyroidism in 25 cases and hyperthyroidism in 16 patients. In this study 70 patients were males and 70 were females. Females (44.28%) had high incidence of thyroid disorders than males (17.14%). Sub–clinical hypothyroidism was more common among elderly (39.02%). Elderly females had high incidence of sub–clinical hypothyroidism (17.14%). Clinical features of hyperthyroid were present in 16 patients. Patients with hyperthyroidism had a poor glycemic control. Duration of diabetes had no relation with incidence of thyroid disorders. Patients with uncontrolled diabetes with micro vascular complication had sub– clinical hypothyroidism.

CONCLUSION – Prevalence of thyroid disorders in Diabetics was 31.42%. Elderly population had more incidence. Sub–clinical hypothyroidism was more common among females. Diabetics with hyperthyroidism had poor glycemic control. Severe diabetic complications were noted in patients with sub–clinical hypothyroidism. Duration of Diabetes had not impact on thyroid dysfunction.