Study of thyroid profile and its association with glycemic control in type II diabetes mellitus

Dr. Prashant Dharme; Dr. Sandip Lambe; Dr. Bhushan Mahajan; Dr. Manisha Achawale

Volume : VII, Issue : VII, July - 2017

Study of thyroid profile and its association with glycemic control in type II diabetes mellitus

Dr. Prashant Dharme, Dr. Sandip Lambe, Dr. Bhushan Mahajan, Dr. Manisha Achawale

Abstract :

Diabetes mellitus is a considered as a group of metabolic disorders characterised by defective regulation of carbohydrate, lipid and protein metabolism. Amid the two types of diabetes, type II is linked with insulin resistance. Insulin and thyroid hormone metabolism can result in functional abnormalities of one another. Therefore, the present study was undertaken in a tertiary care hospital over a period of one and half years with the aim to assess the changes in thyroid profiles of patients with type II diabetes mellitus and to correlate their levels with glycated haemoglobin. Results of the study indicated that mean serum T₃ and T₄ levels were reduced in diabetic patients while mean serum TSH was increased. T₃ levels correlated negatively with glycated haemoglobin whilst TSH correlated positively. Further 33% patients had hypothyroidism among 100 cases indicating hypothyroidism as the most common thyroid dysfunction in type II diabetics.