STUDY ON CLINICAL PROFILE AND OUTCOME IN CRITICALLY ILL PATIENTS WITH RENAL IMPAIRMENT IN A TERTIARY CARE CENTRE

Dr. S. Naga Mohana Rao; Dr. T. Radha Krishna; Dr. G. Swarnalatha Devi

Volume : IX, Issue : I, January - 2019

STUDY ON CLINICAL PROFILE AND OUTCOME IN CRITICALLY ILL PATIENTS WITH RENAL IMPAIRMENT IN A TERTIARY CARE CENTRE

Dr. S. Naga Mohana Rao, Dr. T. Radha Krishna, Dr. G. Swarnalatha Devi

Abstract :

Background: Acute kidney injury (AKI) is a common clinical problem in intensive care unit (ICU) patients and independently predicts poor outcome and is one of the major cause of in–hospital mortality rates globally. The current study was conducted to study the etiological profile, severity and management of acute kidney injury. Methods: The study was a prospective study, conducted in the department of General medicine, ASRAM Medical College during the period of November 2016 to November 2018. The study population included all the patients admitted to Intensive Care Unit (ICU) and having AKI. All the study participants were recruited to the study by convenient sampling. Descriptive analysis was carried out by frequency and proportion for categorical variables. Results: A total of 179 subjects were included. Participants were almost uniformly distributed in each of a decadal age group till above 60 years. Males (60.3%) were slightly higher than females (39.7%). Oliguria was present in 72.62% of the study population. The most common etiology were Sepsis, Acute diarrheal disease. Diabetes Mellitus was the major co morbidity associated with AKI. As per KDIGO criteria Stage 1 constitutes 46%, where as Stage 2,3 contributes to 32% and 22% respectively. Almost all the patients in stage 1 AKI were managed conservatively, most of the patients with Stage 2 were treated with Renal replacement therapy(RRT). All the patients in Stage 3 were treated with RRT. Mortality is more among patients with KDIGO stage 2,3. Meticulous efforts to reduce AKI should be undertaken particularly in critically ill patients. Conclusions: Acute kidney Injury (AKI) can be a consequence of varied aetiologies and all the age groups and both the genders at risk of developing it. KDIGO criteria can be a useful tool in guiding the management and predicting the prognosis. Meticulous efforts to reduce AKI should be undertaken particularly in critically ill patients.