STUDY THE CORRELATION OF HYPERPROLACTINEMIA, THYROID DISORDERS AND MENSTRUAL PATTERN IN INFERTILE WOMEN

Dr. Nida Ansari; Dr. Amita Yadav; Dr. Nishita Chaudhari

Volume : X, Issue : IV, April - 2020

STUDY THE CORRELATION OF HYPERPROLACTINEMIA, THYROID DISORDERS AND MENSTRUAL PATTERN IN INFERTILE WOMEN

Dr. Nida Ansari, Dr. Amita Yadav, Dr. Nishita Chaudhari

Abstract :

Objective : To "Study the correlation of Hyperprolactinemia, Thyroid Disorders And Menstrual Pattern in Infertile Women" Method :– The present study was conducted on 100 women (50 infertile women and 50 fertile women) attending the outpatient and inpatient Department of Obstetrics and Gynaecology in associated hospitals of MOTI LAL NEHRU MEDICAL COLLEGE PRAYAGRAJ over a period of twelve months during the year 2018–2019. Taking all aseptic and antiseptic precautions, 5 milliliters of fasting venous sample was obtained in the morning of day3 of menstrual cycle for serum biochemical analysis. Serum was separated and stored for further analysis. Estimations of serum prolactin, Serum FT3, FT4, TSH are done by using BIO–RAD 680 ELISA microplate reader version 1.7 . The incidence of hyperprolactinaemia and thyroid disorders and menstrual irregularities was studied. The association between thyroid dysfunction, levels of serum prolactin and menstrual status were reviewed. Results:– The majority of the infertile and fertile women were euthyroid and had normal prolactin level. In infertile group, the prevalence of hypothyroidism and hyperprolactinemia was slightly higher in the infertile group in comparison with that of the fertile group. There was a positive correlation between serum hypothyroidism and prolactin hyperprolactinemia in the infertile subjects (06%). P= <0.05. Hyperprolactinemia was depicted in 28% of the infertile women and hypothyroidism was found in 22%. Menstrual complaints were found in 54% cases Conclusions:– In this study there is a positive correlation between increased prolactin levels and hypothyroidism and such patients’ exhibit ovulatory failure. All patients with infertility should undergo prolactin levels and thyroid profile. . Problems in infertility are challenging and taxing to the clinician which can be solved just by tackling some simple endocrinological conditions like hyperprolactinaemia and thyroid disorders.