Volume : IX, Issue : VIII, August - 2019

SURVIVAL ANALYSIS AND VISUAL OUTCOME OF CORNEAL TRANSPLANT IN NORTH EAST INDIA

Pushpita Das, Dr. Jonali Gogoi

Abstract :

The public health significance of corneal transplantation in dealing with corneal blindness in the developing world would depend upon the survival rate of transplant. This study was done to analyze the survival rate of corneal transplant in North East India and to evaluate the influence of various risk factors on transplant survival. The records of a series of 65 cases of corneal transplants carried out during 2018–19. The Kaplan–Meier method was used to determine one year survival rate of corneal transplant performed for the various categories of postoperative cases. Cox proportional hazard regression was used to assess how different categories of surgeries, socioeconomic status, age, sex, quality of donor cornea influenced transplant survival. The effect of these variables on visual outcome was assessed using multiple logistic regression. The survival rate was highest if the corneal transplant done by Descemet Stripping Endothelial Keratoplasty and lowest for Patch Graft surgery. There is a decrease in hazard ratio by 73% for Descemet Stripping Endothelial Keratoplasty surgery. Patients with lower socioeconomic status had higher relative risk of transplant failure. Patients less than 30 years of age had relatively higher risk of transplant failure. Female patients had relatively higher risk of transplant failure as compared to male patients. Higher relative risk of transplant failure was associated with the use of fair quality donor cornea for transplantation compared with excellent and good quality donor cornea. Reasonable success with corneal transplantation is possible in the developing countries if data from this part of world regarding different survival rate for the various categories of surgeries and the influence of risk factors on transplant survival and visual outcome are taken into account while determining priority for transplant cases in the present situation of limited availability of donor cornea.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

SURVIVAL ANALYSIS AND VISUAL OUTCOME OF CORNEAL TRANSPLANT IN NORTH EAST INDIA, Pushpita Das, Dr. Jonali Gogoi INDIAN JOURNAL OF APPLIED RESEARCH : Volume-9 | Issue-8 | August-2019

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