Synthesis  and In vitro antimicrobial activity of N–[4–chloro–6–(morpholin–4–yl)–1,3,5–triazin–2–yl]–2–methylquinolin–8&n

Anil Rathavi; M. K. Thakor

Volume : IV, Issue : VIII, August - 2014

Synthesis and In vitro antimicrobial activity of N–[4–chloro–6–(morpholin–4–yl)–1,3,5–triazin–2–yl]–2–methylquinolin–8&n

Anil Rathavi, M. K. Thakor

Abstract :

A variety of N–[4–chloro–6–(morpholin–4–yl)–1,3,5–triazin–2–yl]–2–methylquinolin–8–amine,G were synthesized by using 2–methylquinolin–8–amine, morpholine and cyanuric chloride. And the structures of these compounds were confirmed by IR, NMR (1H & 13C) spectral analysis. The newly synthesized compounds were also evaluated for antimicrobial activity against variety of bacterial strains and some of these compounds have shown significant antibacterial and antifungal activities.