Synthesis of Pyrazolyl bis indolyl methane and its derivatives using Novel clay catalyst

Ismail Shaikh; Dr. Gajanan Sanap; Dr. Mazahar Farooqui; Dr. Syed Abed

Volume : IX, Issue : VI, June - 2019

Synthesis of Pyrazolyl bis indolyl methane and its derivatives using Novel clay catalyst

Ismail Shaikh, Dr. Gajanan Sanap, Dr. Mazahar Farooqui, Dr. Syed Abed

Abstract :

The present paper gives the application of Novel Clay material obtained from Bashir farm Jatadevale, Tq Pathardi; Dist. Ahmednagar for the synthesis bis indolyl methane derivatives from 1, 3–diphenyl–1–H–pyrazole–4–carboxaldehyde was reacted with indole to form a new species of biologically active moiety to gives very clean and good product. Additionally keeping the view of biological and medicinal properties of pyrazoles and the potential chemistry of indole hence the chemistry of both moieties are synthesized by condensation of these two in search of designing biological active compounds that could aggressively work against bacterial species and cancer cell