SYNTHESIS, STRUCTURAL ANALYSIS AND BIOLOGICAL PROPERTIES OF Mn(II), Co(II), Ni(II) AND Cu(II) COMPLEXES OF SCHIFF'S BASE LIGAND

Ravikant; Sulekh Chandra

Volume : VIII, Issue : XII, December - 2018

SYNTHESIS, STRUCTURAL ANALYSIS AND BIOLOGICAL PROPERTIES OF Mn(II), Co(II), Ni(II) AND Cu(II) COMPLEXES OF SCHIFF'S BASE LIGAND

Ravikant, Sulekh Chandra

Abstract :

In this research work, the acyclic nitrogen (N) and oxygen (O) donor atoms containing Schiff’s base ligand (L) acetophenonenicotinichydrazone has been derived. Ligand (L) is prepared from acetophenone and nicotinic hydrazide by following condensation reaction and its Mn(II), Co(II), Ni(II) and Cu(II) complexes also prepared and structural analysis carried out by elemental analyses, IR, UV–Vis., mass, ¹H–NMR and EPR spectral studied. The ligand (L) behaves as a bidentate ligand and coordinates to metal ions via nitrogen and oxygen donor atoms and complexes have mononuclear construction. Cu(II) complex exhibit distorted octahedral geometry, whereas an octahedral geometry is suggested for all other complexes. Ligand and complexes are evaluated to examine inhibition potential against bacterial and fungal strains and the assay indicated that the metal complexes exhibited remarkable antibacterial and antifungal activities against tested microorganism.