Volume : IX, Issue : IV, April - 2019

Systemic lupus erythematosus. molecular basis disease, Part I

Eliseo Ruiz Bedolla, Briceida Lopez Martinez, Israel Parra Ortega

Abstract :

The exact etiology of systemic lupus erythematosus(SLE) is unknown and the prognosis remains poor. Multiple genes contribute to disease susceptibility. The genetic factors play an important role in the predisposition of the disease however certain environmental factors are required to trigger the disease. From years 1950 has been observed than there is some relation among the activity of enzyme acetyltransferase and the presence of SLE; has been done researches finding some disorders in structure of collagen during disease and also it was observed changes of enzymes activity in blood as so changes on levels of amino acids in blood and urine of patients with SLE and laboratory animals with clinical characteristics of disease. Diagnostic of disease is done usually in advanced state because clinical characteristics of disease are presents after 6 months of started. For this reason is very important to do an early diagnostic of disease and to give a medical treatment timely because some injuries caused by disease are irreversible. Here is presented some of last researches that help to understand the beginning and evolution mechanisms of disease.

Keywords :

Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

SYSTEMIC LUPUS ERYTHEMATOSUS. MOLECULAR BASIS DISEASE, PART I, Eliseo Ruiz Bedolla, Briceida Lopez Martinez, Israel Parra Ortega INDIAN JOURNAL OF APPLIED RESEARCH : Volume-9 | Issue-4 | April-2019

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