Volume : VIII, Issue : VI, June - 2018

THE ANTIPSYCHOTIC ACTIVITY OF AQUEOUS EXTRACT OF WITHANIA COAGULANS FRUITS IN SWISS ALBINO MICE

Dr. Amit S. Kamdi, Dr. Sarika Kokane, Dr. Devesh D Gosavi, Suraj S. Kunchamwar, Suvarna Kalambe

Abstract :

 Background: Schizophrenia is one of the most devastating ain disorders. It is characterized by positive, negative and

cognitive symptoms. The various antipsychotic drugs used today are not devoid of side effects. The Withania coagulans –
a vulnerable species, is not studied much for its central nervous system effects except in late seventies. Therefore, it was thought worthwhile to
investigate anti–psychotic activities of aqueous extract of Withania coagulans fruits.
Methods: Haloperidol induced catalepsy and Cook’s Pole Climb Apparatus for conditioned avoidance response were used for testing the
antipsychotic activity.
Results: There was statistically (p–value >0.05) no significant association between aqueous extract of Withania coagulans fruits with
antipsychotic activity in Swiss albino mice.
Conclusion: Aqueous extract of Withania coagulans fruits did not demonstrate antipsychotic activity in Swiss albino mice.

Keywords :

Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Dr. Amit S. Kamdi, Dr. Sarika Kokane, Dr. Devesh D Gosavi, Suraj S. Kunchamwar, Suvarna Kalambe, THE ANTIPSYCHOTIC ACTIVITY OF AQUEOUS EXTRACT OF WITHANIA COAGULANS FRUITS IN SWISS ALBINO MICE, INDIAN JOURNAL OF APPLIED RESEARCH : Volume-8 | Issue-6 | June-2018


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