The Beneficial Aspect of Ulinastatin in Severe Sepsis due to Splenic Rupture.

Dr. Naresh Sen

Volume : VI, Issue : V, May - 2016

The Beneficial Aspect of Ulinastatin in Severe Sepsis due to Splenic Rupture.

Dr. Naresh Sen

Abstract :

 A 57 year old man underwent an uneventful colonoscopy for black stool with weakness. Three hours later, he had a syncopal episode . Hemoglobin dropped from an initial level from 12.4g/dL to 7.9g/dL. Abdominal CT revealed a 12.8 × 11 × 13cm splenic hematoma with splenic rupture . ECG showed sinus tachycardia. 2D Echo revealed no RWMA, Grade 1 diastolic dysfunction. He was treated for loss blood by bloos transfusion with support of i/v fluids and colloids, antibiotics along with supportive medicines. Massively raised WBC counts was treated with support of two to three oad spectrum antibiotics . Despite of all medical therapy patient did not improved then as per studies we started inj Ulinastatin with same antibiotic support. After 4 days at stable condition, he was shifted to surgical unit and subsequently spleenectomy was performed successfully. After spleenectomy, he became stable with no recurrence of syncope.