The Effect of reperfusion on repolarization index (T peak � T end interval) on the surface Electrocardiogram in patients with ST� segment Elevation Myocardial Infarction and its prognostic significance

Subhrangshu Dey; John Jose; Paul George

Volume : VI, Issue : VII, July - 2016

The Effect of reperfusion on repolarization index (T peak � T end interval) on the surface Electrocardiogram in patients with ST� segment Elevation Myocardial Infarction and its prognostic significance

Subhrangshu Dey, John Jose, Paul George

Abstract :

 Objectives: To determine the effect of reperfusion on TpTe interval in patients with STEMI. Method: Patients with new onset STEMI treated with reperfusion therapy were included. TpTe interval was measured and patients were followed up at 30 days. Major adverse cardiac events were noted. Results: Two hundred and sixteen patients who underwent primary PCI, thrombolysis and rescue PCI were included. The reduction in TpTe interval following reperfusion in all the treatment arms was statistically significant. TpTe interval difference (pre – post) was found to be significantly associated with duration of chest pain at presentation. Pre TpTe interval of more than 100 ms was associated with an increased risk of ventricular arrhythmias. However, it did not predict mortality or heart failure at 30 days. Conclusion: In patients with STEMI undergoing reperfusion, the TpTe interval significantly reduced subsequent to reperfusion therapy. Pre TpTe interval predicted the risk of arrhythmias at 30 days.