The Influence of intrathecal fentanyl on the characteristics of subarachnoid block for emergency caesarean section- A Randomized Controlled Trial

Dr.S.Loganathan

Volume : VII, Issue : XI, November - 2017

The Influence of intrathecal fentanyl on the characteristics of subarachnoid block for emergency caesarean section- A Randomized Controlled Trial

Dr. S. Loganathan

Abstract :

Background; Neuraxial opioids augmenting the analgesia produced by local anaesthetics due to synergistic action and binding directly to opiate receptors

Aim of this study is to compare the influence of intrathecal fentanyl in providing onset of analgesia,muscle relaxation,Quality of surgical anaesthesia,regression time to T₁₂,period of effective analgesia and side effects in emergency caesarean section.

Materials and Methods; This randomized controlled trial conducted among 60 pregnant patients belonging to ASA physical status I in the age of 20–37 years, weight from 51–70kg and height from 140–160cm. Group I patients (study group) received subarachnoid injection of Inj.Fentany1 citrate 15 mg (0.3ml of preservation free drug) along with 2 ml of 0.5% Hyperbaric Bupivacaine over a period of 10 seconds.Group II patient (control group) received subarachnoid injection of 2ml of 0.5% Hyperbaric Bupivacaine along with 0.3 ml of normal saline over a perod of 10 seconds.

Results; The age,height,weight were similar in both groups. Onset anaigesia is faster in gr I (P<0.01). Quality of anaesthesia and muscle relaxation were excellent in gr I.Regression to T₁₂and duration of analgesia is statistically significant in group I. Side effects were similar in both groups.

Conclusion; In this study, it is inferred that addition of 15mg Fentany1 to 2ml of 0.5% Hyperbaric Bupivacaine intrathecally provides a better anaesthesia and analgesia than bupivacaine alone in caesarean section without increasing significant maternal and fetal side effects.