The Prognostic significance of Red cell distribution width (RDW) and Neutrophil–Lymphocyte Ratio (NLR) in Acute Pancreatitis: Identification of an Optimal values

Dr. K. S. Raghavan; Dr. R. Ponraj

Volume : IX, Issue : V, May - 2019

The Prognostic significance of Red cell distribution width (RDW) and Neutrophil–Lymphocyte Ratio (NLR) in Acute Pancreatitis: Identification of an Optimal values

Dr. K. S. Raghavan, Dr. R. Ponraj

Abstract :

Introduction: “Acute pancreatitis” is usually a self–limiting disease; however, severe form of the disease developed in 25 % of patients & it is associated with a mortality of up to 50 %. Currently available gold standard scoring system for assessment of acute pancreatitis’ is the “Acute Physiology and Chronic Health Evaluation” (APACHE II) Aims and Objectives: The aim of the current study is to investigate the validity of RDW and NLR in predicting outcome, and to determine an optimal cut–off value that would allow division of patients in to mild (MAP) and severe acute pancreatitis (SAP) groups. Results: NLR is increased in patients with severe compared to mild acute pancreatitis Conclusion: Elevation of the NLR during the first 48 h of admission is significantly associated with severe acute pancreatitis and is an independent negative prognostic indicator in AP”