The  Study of Clinical  Profiles  of  Vivax Malaria in Comparison with Falciparum Malaria in Children  at  a Tertiary Care Centre in  Eastern Bihar.

Ankur Priyadarshi; Deepak Kumar; Akhilesh Kumar

Volume : VI, Issue : VI, June - 2016

The Study of Clinical Profiles of Vivax Malaria in Comparison with Falciparum Malaria in Children at a Tertiary Care Centre in Eastern Bihar.

Ankur Priyadarshi, Deepak Kumar, Akhilesh Kumar

Abstract :

 Background: Malaria remains an important cause of morbidity and mortality in children and adults in countries where it is endemic. Malaria due to Plasmodium vivax (P. vivax) is usually thought to be causing benign malaria with low incidence of complications as compared to P. falciparum but severe malaria due to P. vivax infection is increasingly observed now a days. Organ failure in vivax malaria is caused by mechanisms of inflammation as well as sequestration. In this study we have compared the clinical profiles complications in vivax malaria with those in falciparum malaria. Objectives: this study was done to compare the clinical profiles and complications of P. vivax with P. falciparum malaria mono infection in children. Material and Methods: This retrospective observational study included malaria patients who were admitted to paediatric indoor ward of J.L.N. Medical college hospital, Bhagalpur, a tertiary care teaching hospital, in eastern Bihar, during a period from March 2015 to March 2016. Inclusion criteria were patients of age group <12 years in whom either P. falciparum or P. vivax was positive on rapid malaria antigen test or peripheral blood smear. Patients showing mixed infections were excluded from study. Results. A total of 75 subjects (mean age 5.5±3.3 years) were included in the study. It consisted of 43 cases of vivax malaria and 32 cases of P falciparum. The P. vivax cases consisted of 32 (74.4%) males and 11 (25.5%) females while P. falciparum cases consisted of 14 (43.7%) males and 18 (56.3%) females. There was no statistical significant difference found between clinical profiles as well as complications such as anaemia, thrombocytopenia, liver and renal dysfunction, ARDS, and cereal malaria between P. vivax and P. falciparum. Conclusion. The present study conclude that P. vivax mono infection tends to have as similar clinical course and complications as compared to malaria due to P. falciparum mono infection in children.