Volume : IX, Issue : III, March - 2019

THE UTILITY OF TOTAL LEUCOCYTE COUNT IN DENGUE

Saurabh Shrivastava, Ramveer Rajput

Abstract :

Background: Dengue infections are public health concerns in India, where they occur in epidemics and have a high mortality in the advanced stages. Clinical features are nonspecific, and diagnosis is supported by lab features. One of these lab tests include total leucocyte count–easily available, simple and cost effective which is useful in small rural set ups for early diagnosis and prognosis of dengue. Leucopenia is caused by bone marrow suppression by virus in acute phase and is due to decrease in polymorphs. The aim of this study is to analyse the importance of total leucocyte count patterns in dengue and assess its utility as early marker of dengue and prognostic indicator of severe dengue. Methods: A total of 82 serologically proven cases of dengue with total white cell counts (blood counts obtained by 3 part Automated hematology analyser & correlated with peripheral smear) during 6 months from May to November 2018 were analysed. Results: In our study, most cases were noted in the younger age group with a male predominance. The range of total leucocyte count was 0.8x109/l to 13.6x109/l. Most (42.7%) had leucopenia, normal counts was noted in 39%. 57.1% had mild leucopenia, 51.4% of leucopenia cases were associated with severe thrombocytopenia. 51.4% of leucopenia cases were NS1 positive while only 17.2% were antibody positive. Conclusions: Total leucocyte count is one of the simple, easily available, cost effective tests useful in small rural set ups for early diagnosis and prognosis in dengue and helps reduce the morbidity and mortality of dengue.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

THE UTILITY OF TOTAL LEUCOCYTE COUNT IN DENGUE, Saurabh Shrivastava, Ramveer Rajput INDIAN JOURNAL OF APPLIED RESEARCH : Volume-9 | Issue-3 | March-2019

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