Volume : IX, Issue : VI, June - 2019
Therapeutic Plasma Exchange: Gold standard treatment for atypical hemolytic uremic syndrome in children in India.
Sheetal A. Chandak, Hansa M Goswami. , Aruna V. Vanikar
Abstract :
Introduction: Atypical HUS (aHUS) is a serious disease caused by disorder of the complement system or due to genetic etiology. Therapeutic Plasma Exchange (TPE) is a preferred treatment for aHUS. Material and methods: This was a retrospective study carried out over pediatric patients with aHUS between 2017 and 2018. One to 1.5 plasma volume was removed during every TPE and replaced with fresh frozen plasma. Clinical parameters were monitored pre and post TPE. Results: 119 TPE were carried out in 15 patients. Average pre TPE and post TPE platelet count were 96.53 ± 75.33 x 109/L and 116.80 ± 80.30 x 109/L( p=0.34) Average pre TPE and post TPE hemoglobin was 6.76 ± 1.79 gm/dL and 8.13 ± 2.12 gm/dL (p=0.5) and pre TPE and post TPE serum creatinine was 1.43 ± 1.85 and 0.70 ± 0.63 mg/dl (p<0.01). Conclusion: TPE is a safe procedure in the treatment of aHUS.
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DOI : 10.36106/ijar
Cite This Article:
THERAPEUTIC PLASMA EXCHANGE: GOLD STANDARD TREATMENT FOR ATYPICAL HEMOLYTIC UREMIC SYNDROME IN CHILDREN IN INDIA., Sheetal A. Chandak, Hansa M Goswami., Aruna V. Vanikar INDIAN JOURNAL OF APPLIED RESEARCH : Volume-9 | Issue-6 | June-2019
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THERAPEUTIC PLASMA EXCHANGE: GOLD STANDARD TREATMENT FOR ATYPICAL HEMOLYTIC UREMIC SYNDROME IN CHILDREN IN INDIA., Sheetal A. Chandak, Hansa M Goswami., Aruna V. Vanikar INDIAN JOURNAL OF APPLIED RESEARCH : Volume-9 | Issue-6 | June-2019
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