Volume : X, Issue : II, February - 2020

Thyroid Hormone as a risk factor for miscarriage!!

Dr Yashi Srivastava, Dr Urvashi Barman Singh, Dr Meena Dayal, Dr Shakti Jain

Abstract :

Aim: Abnormal thyroid hormone levels could give rise to increased placentation defects that underlies the association between maternal thyroid dysfunction and adverse pregnancy outcomes. This study was designed to analyze the thyroid hormone profile in the study groups and its possible association with the risk of abortion during pregnancy. Methodology: This was a analytical observational cohort study conducted over a time period of 1 year, on 120 women attending the antenatal clinic in Department of Obstetrics and Gynaecology, Swaroop Rani Nehru Hospital, Prayagraj. The patients were divided into two groups, Group 1 (n = 80) included women with previous history of abortions and group 2 (n = 40,control group) included women with no history of abortions. S.T3, S.T4 and TSH levels were estimated and compared in both the groups. Result: In the present study, the abortion rate was higher in the hypothyroid group as compared to euthyroid group (p < 0.05). TSH was found to be strongly associated with abortion in the cases (p≤ 0.001). TSH levels were significantly higher in women who had an history of previous pregnancy loss than the women who had successful continuation of pregnancy. Conclusion: S.TSH was found to be strongly associated with abortions, mainly in the first trimester, in both the groups. Thus, screening of thyroid dysfunction in early pregnancy has clinical significance and adequate T4 replacement therapy if given in cases of hypothyroidism would help to reduce the risk of miscarriage in these women

Keywords :

Article: Download PDF    DOI : 10.36106/ijar  

Cite This Article:

THYROID HORMONE AS A RISK FACTOR FOR MISCARRIAGE!!, Dr Yashi Srivastava, Dr Urvashi Barman Singh, Dr Meena Dayal, Dr Shakti Jain INDIAN JOURNAL OF APPLIED RESEARCH : Volume-10 | Issue-2 | February-2020

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