Volume : V, Issue : IV, April - 2015

TLC–Bioautography guided screening for compounds inhibitory to Klebsiella pneumoniae from Justicia wynaadensis (Nees) T. Anders

S. U. Ponnamma, K. Manjunath

Abstract :

 The increasing occurrence of opportunistic infections as well as infections caused by multi–drug resistant 

organisms has led to new efforts in the search for novel antimicrobial compounds. Justicia wynaadensis 
is a scandent herb found growing in the forest and estate regions of Kodagu District. The present investigation deals 
with the TLC–Bioautography of the methanolic extract of J. wynaadensis, followed by GC–MS analysis of active fractions. TLC–Bioautography resulted in four clearly visible active spots showing large inhibition zones. The antibacterial 
activity of the methanolic extract of J. wynaadensis against Klebsiella pneumoniae MTCC 3384 could be attributed to 
volatile components such as phytol and to the fatty acids such as myristic acid, palmitic acid, linoleic acid and stearic 
acid. 

Keywords :

Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

S. U. Ponnamma, K. Manjunath TLC–Bioautography guided screening for compounds inhibitory to Klebsiella pneumoniae from Justicia wynaadensis (Nees) T. Anders Indian Journal of Applied Research, Vol.5, Issue : 4 April 2015


Number of Downloads : 844


References :