TO EVALUATE THE EFFICACY OF TOPICAL 0.03% TACROLIMUS OINTMENT FOR TREATMENT OF REFRACTORY VERNAL KERATOCONJUNCTIVITIS

Charu Jain; Anurag Makkar; V.K. Malik

Volume : VII, Issue : III, March - 2017

TO EVALUATE THE EFFICACY OF TOPICAL 0.03% TACROLIMUS OINTMENT FOR TREATMENT OF REFRACTORY VERNAL KERATOCONJUNCTIVITIS

Charu Jain, Anurag Makkar, V. K. Malik

Abstract :

Introduction– Conjunctivitis is the most common eye disease worldwide. As the treatment of vernal keratoconjunctivitis is still a dilemma, there is a need for devising a treatment modality that is safe as well as effective in refractory vernal keratoconjunctivitis (VKC). Aim– To study the efficacy and safety profile of 0.03% tacrolimus eye ointment in refractory vernal keratoconjunctivitis. Material &methods–70 eyes of 35 patients with refractory VKC were included in the study. 0.03% tacrolimus eye ointment was given two times a day and patients were followed up at 1st,3rd,6th and 12th week . Results– At the end of 12 weeks there was a marked reduction in the mean score of symptoms and signs (p<0.001). The drug was well tolerated and no complication was reported in any patient. Conclusion–0.03% tacrolimus ointment is safe and effective in treatment of refractory vernal keratoconjunctivitis VKC.