To evaluate the value of CRP and lactate in bowel obstruction as predictor of strangulation.

Dr. Dug Tariq Hassan; Dr. Liyaqat Nazir; Rayees Ahmad Bhat; Dr Shabir Ahmad Dar; Dr. (Prof.) Mohammad Zakiuddin

Volume : IX, Issue : XII, December - 2019

To evaluate the value of CRP and lactate in bowel obstruction as predictor of strangulation.

Dr. Dug Tariq Hassan, Dr. Liyaqat Nazir, Rayees Ahmad Bhat, Dr Shabir Ahmad Dar, Dr. Prof. Mohammad Zakiuddin

Abstract :

Background: Intestinal obstruction is one of the commonest clinical problems encountered in surgical practice. One of the grave complications of intestinal obstruction is strangulation, which requires an emergency laparotomy for management. This study was conducted to emphasise the significance of early estimation of rise in serum C–reactive protein and D– lactate levels. Aims and objective: The aim of this retrospective study was to examine whether various laboratory parameters could predict viability of strangulation in patients with bowel obstruction. Material and Methods: Hospital based prospective study was performed on 50 patients admitted in Shere Kashmir Institute of Medical Sciences, Srinagar in various surgical units with diagnosis of acute intestinal obstruction and underwent explorative Laparotomy. Results: CRP test sensitivity was 84.00%, specificity was 81.67%, PPV was 74.91% and NPV was 87.89% to detected the obstruction with strangulation when using a cut off value of 60 mg/L. D–lactate test sensitivity was 80.00%, specificity was 90.00%, PPV was 84.30% and NPV was 87.10% to detected the obstruction with strangulation when using a cut off value of 4.5 mmol/L. Conclusions: Serum CRP and D–lactate can be useful and reasonable markers for predicting strangulation in cases of acute intestinal obstruction in an emergency setting.