Volume : V, Issue : VIII, August - 2015

Tobacco smoking impact on pregnancy–associated plasma protein–A (PAPP–A) levels in the blood serum of women in first trimester of pregnancy

Magdalena Pasinska, Anita D Browska, Ewelina Lazarczyk, Anna Repczynska, Grzegorz Przybylski

Abstract :

<p><p><p> T The purpose of this paper was to estimate levels of pregnancy–associated plasma protein–A (PAPP–A) in serum blood of smoking and non–smoking women in the first trimester of pregnancy, taking into account its duration, and also age and body weight of pregnant women. Study group consisted of 4473 patients aged 18 to 47 with unifetal pregnancy who underwent first trimester non–invasive screening though blood serum tests. Biochemical parameter levels measurement was conducted through a fully automated immunofluorescence method. We observed that PAPP–A MoM value for a smoking woman was on average 16.0% lower in comparison with the results of a non–smoking woman of the same weight with the standard error 3.5%. Smoking cigarettes by pregnant women decreases PAPP–A MoM level by 16.0% on average in comparison with the results of a non–smoking woman of the same weight.</p></p></p>

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Magdalena PasiÃ¥Æ ¦Ã¥Æ‚¢Ã¥‚¢‚‚¬Ã¥â‚¦Ã‚‚¾ska, Anita DåƄåÆ‚¢Ã¥‚¢‚‚¬Ã¥‚‚¦browska, Ewelina Ã¥Æ ¦Ã¥Æ‚Ã¥‚‚azarczyk, Anna RepczyÃ¥Æ ¦Ã¥Æ‚¢Ã¥‚¢‚‚¬Ã¥â‚¦Ã‚‚¾ska, Grzegorz Przybylski Tobacco smoking impact on pregnancy-associated plasma protein-A (PAPP-A) levels in the blood serum of women in first trimester of pregnancy. Indian Journal of Applied Research, Vol.5, Issue : 8 August 2015


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