Volume : X, Issue : VI, June - 2020

TRANSCRANIAL DOPPLER STUDY OF INTRACRANIAL ARTERIAL RESISTANCE AND VASOREACTIVITY IN TYPE 2 DM WITH STROKE.

Vaibhav Hanumant Bhoyar, Prof. M. Jawahar, Prof. Lakshminarasimhan R

Abstract :

BACKGROUND : The pulsatility index reflects the vascular resistance of intracranial arteries and could therefore be used as an estimate of the severity of vascular damage.similarly T2DM leading to decreased vasomotor reactivity and causing complications like stroke . AIM : The present study aimed to examine the influence of type 2 diabetes mellitus on intracranial vascular resistance in patients with a previous stroke and to assess vasomotor reactivity by eath holding. MATERIAL AND METHODS : Transcranial doppler investigations were performed in 102 patients with previous stroke (40 with T2DM, 62 T2DM), at least 3 months after stroke occurred. Gosling‘s pulsatility index was calculated. The maximum pulsatility suggestive of more pronounced damage. Baseline MCA MFV obtained before and after 30 sec of eath holding and eath holding index calculated. RESULTS : Diabetic patients had a significantly higher pulsatility index than non–diabetic patients in all intracranial arteries. The maximal pulsatility index was also significantly higher in diabetics than in non–diabetics (1.29 +/– 0.37 vs. 1.05 +/– 0.20; p < 0.0001). Among 40 with T2DM and stroke 32 had BHI less than1.5 than without T2DM in which out of 62 only 16 had BHI less than 1.5. CONCLUSIONS: Diabetic patients with previous stroke have a higher pulsatility index than non–diabetic patients with previous strokes, indicating a higher increase in intracranial arterial resistance. Patients with T2DM had lesser BHI index than without T2DM with stroke suggesting lesser vasomotor reactivity in T2DM

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Article: Download PDF    DOI : 10.36106/ijar  

Cite This Article:

TRANSCRANIAL DOPPLER STUDY OF INTRACRANIAL ARTERIAL RESISTANCE AND VASOREACTIVITY IN TYPE 2 DM WITH STROKE., VAIBHAV HANUMANT BHOYAR, Prof.M.JAWAHAR, Prof.LAKSHMINARASIMHAN R INDIAN JOURNAL OF APPLIED RESEARCH : Volume-10 | Issue-6 | June-2020


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