Urinary Albumin to Creatinine Ratio and the Risk for Asymptomatic Peripheral Arterial Disease among Elderly with Type 2 Diabetes Mellitus

Moatasem S. Amer; Mohamed S. Khater; Wessam H. El – Kawaly; Omar H. Omar; Randa A. Reda

Volume : IV, Issue : XII, December - 2014

Urinary Albumin to Creatinine Ratio and the Risk for Asymptomatic Peripheral Arterial Disease among Elderly with Type 2 Diabetes Mellitus

Moatasem S. Amer, Mohamed S. Khater, Wessam H. El Ndash Kawaly, Omar H. Omar, Randa A. Reda

Abstract :

Peripheral arterial disease (PAD) is more prevalent in patients with diabetes mellitus resulting in increased risk of lower extremity amputation and mortality 2. Microalbuminuria is also highly prevalent among diabetic patients and is an indicator for overt nephropathy and early cardiovascular disease but whether urinary albumin excretion rate is a risk factor for PAD or not, this question needs to be answered 10. Methods: 90 elderly subjects were subdivided into 3 groups; first group included 30 elderly diabetic patients without PAD, second group included 30 elderly diabetic patients asymptomatic for PAD but with arterial duplex showing PAD and third group included 30 controls without any health problems. The relationships between urinary albumin to creatinine ratio, high sensitivity C – reactive protein (hs–CRP) and anklachial index were examined. Conclusion: Higher urinary albumin to creatinine ratio and higher CRP levels were risk factors for PAD in elderly diabetic patients asymptomatic for PAD.