Volume : IX, Issue : III, March - 2019

Y-CHROMOSOME MICRODELETION AND ITS DIAGNOSTIC IMPORTANCE IN MALE INFERTILITY.

Dr. G. Rekha, Dr. V. Rajitha, G. Paramesh

Abstract :

To identify chromosomal aberrations of male Infertility cases and to evaluate the patterns of Y–chromosome micro deletion in Male Infertility cases (N=147) attending the infertility clinic. PCR based Y chromosome microdeletion analysis revealed nearly 14.28% (21/147) deletions in the Infertile men with idiopathic infertility, of which 5.4% deletion among Azoospermic men, 2.72% among severe Oligospermic men, 4.08% among Oligospermic men and 2.04% among Asthenozoopermic, Oligoastheno–teratoazoospermic, Astheno–teratozoospermic men. In summary the incidence of AZFc deletion was more frequent in Azoospermic which could be the cause for the severe spermatogenic failure in Subfertile men opting for Assisted reproductive procreation technique. Hence PCR based Y chromosomal microdeletion analysis is essential to prevent the transmission of defective genes to the offspring before the ART

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Y-CHROMOSOME MICRODELETION AND ITS DIAGNOSTIC IMPORTANCE IN MALE INFERTILITY., Dr.G.Rekha, Dr. V.Rajitha, G.Paramesh INDIAN JOURNAL OF APPLIED RESEARCH : Volume-9 | Issue-3 | March-2019

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