IJSR - International Journal of Scientific Research

Dr Mahavir Bagrecha; Dr Sanjay Gabhale

Volume : VIII, Issue : VIII, August - 2019

A Study of Arterial Blood Gases with Chronic Obstructive Pulmonary Disease in A Tertiary Care Hospital

Dr Mahavir Bagrecha, Dr Sanjay Gabhale

Abstract :

Chronic obstructive pulmonary disease (COPD) is a major public health problem. Diseases of the respiratory system affect main lung function i. e. homeostasis of gases. Pathology in any organ of body is associated with its functional compromise. This functional compromise measurement reflects type and severity of that pathology, and its outcome. Similarly measurement of blood oxygen, carbon dioxide and pH may help in assessing type and severity of respiratory pathologies. So this prospective study was aimed to correlate arterial blood gas analysis with severity and outcome of COPD. 47 patients of COPD were selected randomly from OPD. During the treatment of patient periodically ABG was tested to assess the management. Pearson correlation test was done to correlate PaO2, Pa CO2 with spirometry parameters. We found that in COPD patients chronic respiratory acidosis i.e. persistent hypercapnia was common finding. In COPD patients with hypercapnia, alveolar–arterial gradient was not reliable indicator of hypoxaemia. Patients of COPD with cor–pulmonalae are more hypoxaemic and hypercapnic than patients without cor–pulmonalae. In COPD patients there is significant positive correlation of PaO2 with % FEV1 of predicted, and significant negative correlation of PaCO2 with %FEV1 of predicted.