IJSR - International Journal of Scientific Research

N.Trivikram; Dr.S.P.SreedharBhattar

Volume : IX, Issue : I, January - 2020

A study on anti–cancerous capabilities of PTP7 on different cell lines by MTT assay

N. Trivikram, Dr. S. P. Sreedharbhattar

Abstract :

In the present cancer advancing days, scientific investigation was catch up in studying the protein peptides involving in signalling pathways in regulating cancer cell lines development and proliferation. In our current we focused on an essential peptide protein tyrosine phosphatase, which plays an important role in signalling path way. This work evaluated the efficiency of PTP7 against 3 cancer cell lines renal, east and prostate cancer lines by MTT assay. PTP 7 on Renal cancer cell line (HTB9) shown 73.660%, east cancer cells (MFC–7) shown 79.313% and Prostate cancer cells (PC–3) shown 87.559 % of viability by MTT assay. The advancing of protein tyrosine protease is concluded to have good viability over can cell lines, as it can further investigated in controlling of cancer.