Volume : II, Issue : III, March - 2013

A UV–Visible Spectrophotometric Determination of atenolol in Pharmaceutical Formulations

Nagaraja Setty K, Chakravarthi I. E

Abstract :

A simple, accurate, rapid and sensitive spectrophotometric method has been developed for the determination of atenolol in pharmaceutical dosage forms. In this method 2,3–dichloro–5,6–dicyano–p–benzoquinone (DDQ) was utilized for determination of atenolol forming charge transfer complex with maximum absorbance at λmax 405 nm. Optimization of the reaction conditions has been investigated. Obediance to Beer‘s law permitted the assay of atenolol in their dosage form. Statistical analysis of the obtained results showed no significant difference between the proposed method and other official and reported methods as evident from the t–test. The proposed method is simple, rapid accurate, precise, reproducible, and economic and can be used for routine quantitative analysis of atenolol in pure and tablet dosage form.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Nagaraja Setty K, Chakravarthi I. E A UV-Visible Spectrophotometric Determination of atenolol in Pharmaceutical Formulations International Journal of Scientific Research, Vol.II, Issue.III March 2013

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