IJSR - International Journal of Scientific Research

L.Jagapriya; N. Shaista jabeen; S. Nathiya; R. Ezhilarasi; K. Devi

Volume : VI, Issue : XII, December - 2017

CYTOTOXICITY EFFECT OF SYZYGIUM CUMINI SEED AND NIGELLASATIVASEEDEXTRACTS ON HUMAN HEPATO CELLULAR CARCINOMA

L. Jagapriya, N. Shaista Jabeen, S. Nathiya, R. Ezhilarasi, K. Devi

Abstract :

The purpose of this study was to assess the cytotoxicity effect of SC and NS in the human liver hepatocellular carcinoma, HepG2. The test items SC and NS has been tested in the MTT assay for the cell growth inhibition property in human hepatocellular carcinoma cell line, HepG2. The results revealed that the compounds does not showing any much toxicity to the tested cell line. However compound Syzygium cumini shows slightly higher toxicity than compound Nigella sativa at the higher concentration tested wells. Cells treated with S. cumini and N. sativa images shows no significant difference between the same concentrations of compound treated wells.To evaluate the test items (S.cumini and N.sativa) cytotoxic property using HepG2 cell line.S.cumini and N.sativa Concentration: 1000, 300, 100, 30, 10, 3.0, and 1.0 μg/ml. Cell line: HepG2 (Human Liver hepatocellular carcinoma).