IJSR - International Journal of Scientific Research

J. Vasundharamma; Dr. G. Meerabai

Volume : VI, Issue : VI, June - 2017

Effect of ethyl acetate aqueous extract of Acanthospermum hispidum DC. on hyperglycemic condition in STZ induced diabetic rats

J. Vasundharamma, Dr. G. Meerabai

Abstract :

This study aimed to testify the anti hyperglycemic effect of ethyl acetate aqueous extract of Acanthospermum hispidum, DC. .a member of the family Asteraceae. In this study it is investigated in both normal and streptozotocin induced diabetic rats and compared this effect with the effect of glibenclamide, a standard hypoglycemic agent. Blood glucose and urine sugars are estimated. Oral glucose tolerance test is conducted. Insulin level is estimated in Plasma of normal and STZ induced diabetic rats by ELISA method. Insulin is assayed. It is found that the extract of A.hispidum normalized the hyperglycemic condition in STZ induced diabetic rats, because of its potent anti hyperglycemic activity. This study confirmed that A. hispidum plant can mitigate and assist in combating diabetic complications.