IJSR - International Journal of Scientific Research

Dr. Roobina Khan; Dr Binjul Juneja; Prof Nishat Afroz; Prof Sheelu Shafiq; Prof Syed Harris Hasan

Volume : VIII, Issue : VIII, August - 2019

EFFECT OF VITAMIN D ON SEX HORMONES IN PATIENTS WITH TYPE 2 DIABETES MELLITUS

Dr. Roobina Khan, Dr Binjul Juneja, Prof Nishat Afroz, Prof Sheelu Shafiq, Prof Syed Harris Hasan

Abstract :

Almost one billion individuals worldwide have low circulating Vitamin D levels. Vit D has been linked to everything from cancer and heart disease to diabetes. An active metabolite of Vit D,1,25 dihydroxy Vit D is said to regulate various enzymes involved in the steroid hormone production, both adrenal steroid and sex hormones, together with the sex hormone signaling. The present study was hospital based prospective, case control study, conducted in 112 diagnosed patients of type 2 diabetes mellitus on oral hypoglycaemic agents, to observe the effect of vitamin D on sex hormone (estrogen and testosterone). Out of 112, 62 diabetic patients had hypovitaminosis and formed group A and 50 diabetic patients had optimal levels of serum vitamin D forming group B, the control group. We observed that supplementation of vitamin D helps in regulating the levels of sex hormones such as testosterone in type 2 diabetes mellitus patients.