IJSR - International Journal of Scientific Research

Dr. Varsha V. Andhare; Prachi S. Dandge

Volume : VIII, Issue : VII, July - 2019

HISTOLOGICAL STUDY OF THE KIDNEY OF ALBINO MALE RATS FED WITH BT AND NON BT COTTON SEED

Dr. Varsha V. Andhare, Prachi S. Dandge

Abstract :

The development of GE crops like Bt cotton is one of the main achievement of modern plant biotechnology. The present study was performed to investigate the histological effects of Bt cotton seed and non Bt cotton seed in the kidney of male albino rat. The male albino rats were divided into 3 equal groups depends upon the diet given to them. The control group was given normal diet with 50% of carbohydrate (wheat), 30% protein (casein) and 20% fat (groundnut powder). Experimental and non–experimental groups were given same proportion of diet but fat content was replaced by 20% of powdered Bt and non Bt cotton seeds respectively for 60 days. The animals were anesthetized; kidneys were extracted for histological studies. In the kidney of experimental group male rats the changes were noted i.e. focal glomerular atrophy, multifocal necrotic changes, and multifocal congestion with focal hemorrhages.