IJSR - International Journal of Scientific Research

Dr. Babita Sahu; Dr. Srikanth Guduguntla; Dr. Sachin B Mangalekar; Dr. Sunaina Shetty; Dr. Priyanka Thakur; Dr.Supriya Mishra

Volume : III, Issue : II, February - 2014

Quorum Sensing and Quorum Quenching Facebook of Microbial World

Dr. Babita Sahu , Dr. Srikanth Guduguntla, Dr. Sachin B Mangalekar, Dr. Sunaina Shetty, Dr. Priyanka Thakur, Dr. Supriya Mishra

Abstract :

Dental Plaque is an example of biofilm leading to periodontal disease and dental caries. Many Gram-positive and Gram-negative bacteria communicate using small diffusible signal molecules called autoinducers. This process, known as quorum sensing, links cell density to the expression of genes as diverse as those associated with virulence factors production of pathogens, bioluminescence, antibiotic production, sporulation of biofilm formation. The interference with these signaling systems, also known as Quorum Quenching, represents a promising strategy to tackle bacterial infections. Recent advances have revealed that bacteria are not only limited to communicate within their own species but also are capable of “listening in” and “oadcasting to” unrelated species to intercept messages and coerce cohabitants into behavioral modification for increase in cell population and density