IJSR - International Journal of Scientific Research

Nidhi Singh; Manoj Kumar; Prakash Kumar; Ashok Kumar Sharma

Volume : V, Issue : X, October - 2016

Serum Triglyceride Lowering effect of Cilnidipine in Patients of Essential Hypertension in RIMS, Ranchi

Nidhi Singh, Manoj Kumar, Prakash Kumar, Ashok Kumar Sharma

Abstract :

Background: The relation between Hypertension and Dyslipidemia has been established by many epidemiological studies. Calcium channel blockers are one of the first line drugs for newly diagnosed patients of essential hypertension. Cilnidipine is a new calcium channel blocker act by blocking both L & N type of calcium channel possesses additional beneficial effects apart from lowering blood pressure. Method:The Aim of this study is to evaluate the effectiveness of Cilnidipine in patients of essential hypertension and its effects on lipid profile. Out of 45 enrolled patients 37 completed the study. Cilnidipine started at 10 mg/day, and then adjusted to 5–20 mg/day. Results:After 12 weeks of study patients of showed significant reduction in sBP, dBP, mBP, heart rate and triglyceride from base line (p value < 0.00). Conclusion:In clinical setting where both hypertension and hypertriglyceridemia coexist Cilnidipine can be promising drug of choice.