Volume : VII, Issue : II, February - 2018

STUDIES AND SYNTHESIS OF BIOLOGICAL ACTIVE MIXED LIGAND Zn (II) COMPLEXES

Dinesh V. Bhagat, Vikas V. Vaidya

Abstract :

 

Synthesis of mixed ligand  Zn (II) complexes of  the type [M (Q) (L)].2H2O have been carried out by  using 8–hydroxyquinoline  (HQ) as a primary ligand & N–and/or O–donar amino acids (HL) such as

L–valine, L–asparagine, L–glutamine, L–arginine and L–methionine as a secondary ligands. The characterization of  metal complexes has been carried out on the basis of elemental analysis, electrical conductance, room temperature, magnetic susptebility measurements, spectral & thermal studies.

            The electrical conductance studies of the complexes in DMSO (dimethyl sulphoxide) in 10–3 M concentration indicate their non–electrolytic nature. Room temperature magnetic susceptibility measurements specify that Zn (II) complexes are diamagnetic in nature . Electronic absorption spectra of the complexes show intra–ligand, charge transfer & d–d transition respectively. The thermal analysis data of the complexes indicate the presence of co–ordinated water molecules. FTIR spectra shows bonding of metal ions through N– and O– donar atoms of ligands molecules. Tube dilution and Agar cup methods were implemented  for  study the antibacterial activity of the complexes against the pathogenic bacteria Staphylococcus aureus, Corynebacterium diphtheriae, Salmonella typhi and Escherichia coli. The results have been compared with those of tetracycline, which was screened simultaneously & indicated mild antibacterial activity of the complexes.

Keywords :

Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

DINESH V.BHAGAT, VIKAS V. VAIDYA, STUDIES AND SYNTHESIS OF BIOLOGICAL ACTIVE MIXED LIGAND Zn (II) COMPLEXES, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-7 | Issue-2 | February-2018


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